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What is the difference between Serum and Plasma?

We explain that what is the difference between Serum and Plasma? Plasma and serum are the names of two different but equally important components of blood. Each of them has important characteristics that play crucial roles when analyzing blood samples.what is the difference between serum and plasmaplasma

What is blood serum?

The serum is the liquid obtained from the blood when this is then allowed to coagulate extraction. It is used in a number of clinical and biochemical trials. Importantly, serum is not a part of the blood, but is the result of allowing the blood to clot outside the body. Therefore, it is formed after blood clotting. The serum helps in the diagnosis of diseases such as blood pressure, sugar, cholesterol, etc.what is the difference between serum and plasma

How is serum obtained from blood?

The serum comes from blood obtained from an arterial or venous puncture without anticoagulant. The blood is allowed to clot and the fibrin, blood cells and platelets are separated from the serum by means of centrifugation.

To obtain the serum, wait at least one hour at room temperature before centrifugation, to ensure that the coagulation process is carried out in its entirety.

What is blood plasma?

Plasma is the medium of the blood in which there are different types of blood cells. Red blood cells, white blood cells, and other blood components are suspended in the plasma..

  • Plasma is the liquid part of the blood. It contains the clotting agent fibrinogen, which prevents excessive blood flow during an injury. It also contains proteins that help in the transport of glucose and other nutrients to different parts of the body.
  • Plasma helps regulate body temperature.
  • It is also responsible for controlling blood pressure.
  • Plasma is obtained in the upper layer during centrifugation. It separates to increase longevity up to years and also to facilitate its transport from one place to another.
  • A cellular component : includes white blood cells, red blood cells, and platelets.
  • An acellular component : made up of plasma , where proteins are dissolved, such as coagulation factors, albumin, lipoproteins, calcium, sodium, potassium, hormones and glucose, among other compounds.

Plasma is obtained from blood obtained with an anticoagulant, a compound that prevents clotting. Blood is drawn by venipuncture and placed in vacuum-sealed tubes containing the required amount of anticoagulant.what is the difference between serum and plasmawhat is the difference between serum and plasma

Commonly used anticoagulants are EDTA, heparin, or citrate. The use of each depends on the type of chemical tests to be carried out. what is the difference between serum and plasma

The plasma is then separated from the solid elements in the blood by means of centrifugation. Plasma can be obtained quickly as it does not need a waiting time to produce clotting, as in the case of serum. what is the difference between serum and plasma

serum vs plasmaWhat Is The Differences Between Serum And Plasma what is the difference between serum and plasma

Plasma and serum are derived from the liquid portion of the blood, however the difference between plasma and serum is quite obvious. Read on to find out how they differ.

Blood is a fluid connective tissue that travels throughout the body carrying necessary nutrients, oxygen, and metabolic waste. It also participates in the regulation of body temperature and pH levels by interacting with acids and bases.

Blood is mainly made up of RBC (red blood cells), WBC (white blood cells), plasma, and serum. Plasma and serum are the main components of blood and are used routinely in blood group analysis experiments to determine the blood group of the patient. what is the difference between serum and plasma

Plasma and serum can be separated by centrifugation of blood on the basis of weight, size, and density. Serum is the fluid that is obtained after allowing the blood to clot, while plasma is obtained after treating the blood with anticoagulant compounds.

what is the difference between serum and plasmaDifference between plasma and serum

Serum and plasma are obtained from the liquid portion of the blood that is obtained when cells are collected. However, there is a notable difference between plasma and serum. Serum is the fluid that remains after blood clotting. Whereas, plasma is the liquid that remains when anticoagulant is added to prevent clotting. what is the difference between serum and plasma

Difference between plasma and serum By comparison table

Below are the important differences between plasma and serum:

Plasma Serum
Straw-colored transparent liquid portion of blood. An undiluted fluid, the extracellular portion of blood.
It is made up of serum and clotting factor. It is the part of the blood that lacks clotting factor.
It is acquired after centrifuging blood with the anticoagulant. It is acquired after centrifuging coagulated blood.
Anticoagulant is required to obtain plasma from the blood sample. Anticoagulant is not required to separate serum from blood sample.
It consists of 55% of the total blood volume. Lower volume compared to plasma.
Comparatively easier and less time is required to separate plasma from blood sample. Difficult to separate serum from blood sample. It is a time consuming process.
Contains fibrinogen. It lacks fibrinogen.
It consists of 92% water with proteins, salts, lipids and glucose. It consists of 90% water with dissolved hormones, proteins, minerals and carbon dioxide.
It has a density of 1.025 g / ml It has a density of 1,024 g / ml.
It has a long service life. It can be kept for up to ten years. It has a short shelf life. It can only be kept for a few months.
Plasma is the main medium for the transport of excretory products. An important source of electrolytes.
Cells are freely suspended in plasma. Cells stick together by forming clots.
This is the liquid, cell-free part of the blood. If red blood cells and white blood cells are removed from a blood sample, what remains would be the plasma. Plasma is the main component of blood, representing up to 55% of the total volume. As for the serum, this is the remaining blood component once the clotting process has taken place. It can be said, in fact, that it is the equivalent or the remainder of plasma but without the substances that allow coagulation to occur.
Fibrinogen is a protein that is essential for blood clotting. Plasma contains this substance in addition to other clotting agents. Blood serum, on the other hand, is blood plasma that no longer contains fibrinogen or any other clotting agents.

Frequent Questions: Factors in plasma and serumFrequent Questions

What are the advantages of plasma over serum? what is the difference between serum and plasma

Plasma contains the most widely used anticoagulant heparin. It acts through a complex that forms with antithrombin-III. Antithrombin III is a protein that prevents blood clotting.

What is serum?

Serum is the plasma from which clotting factors have been removed. what is the difference between serum and plasma

What is the difference between blood and plasma? what is the difference between serum and plasma

Plasma is the translucent part of the blood that is not red blood cells, white blood cells, platelets, and other cellular components. Helps blood clot and is made up of 90% water.

How is plasma collected from the body?

Collecting plasma is time consuming. It takes about an hour to collect plasma from the body. Blood is drawn from the body with the help of a needle placed in the arm, and the plasma is separated from the red blood cells, white blood cells, and platelets. what is the difference between serum and plasma

How is serum taken from the blood?

To separate the serum from the blood, it must be centrifuged at 1600 g for 10 minutes at room temperature. These factors reduce platelet contamination. You should grab the serum that is on top of the centrifuged tube and avoid grabbing the gel or clot.

Why is serum testing done?

Serum is made to measure the amount of protein albumin in the blood. When the kidney begins to fail, albumin begins to leak into the urine. The serum test helps diagnose liver and kidney abnormalities. what is the difference between serum and plasma

What is blood serum?

The hematic serum or blood serum is the result of allowing it to clot and eliminate the clot. It is an equivalent to blood plasma, but without involving the proteins seen in coagulation (fibrinogen). what is the difference between serum and plasma

What are the proteins found in the blood?

  • Globulins
  • Fibrinogen
  • Albumins
  • Lipoproteins.

What components does the serum have?

It contains electrolytes, water and other substances such as carbon and some expanding polysaccharides.

What is blood plasma and what is it for?

As mentioned, plasma is a substance rich in platelets so it is very useful in the medical field. In the orthopedic area, it is used for plastic and dental surgery, it also serves in the field of dermatology, its efficiency is given by its capacity in wound healing and skin rejuvenation.

What is the composition of the blood?

Blood in the human adult body is distributed as follows: 4.5 and 6 liters of blood. 55% is plasma and 45% is red blood cells, white blood cells and platelets. what is the difference between serum and plasma

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