We explain what enzymes are and their structure. In addition, how they are classified and how these proteins act.
Enzymes are a group of proteins responsible for catalyzing (firing, accelerating, modifying, slowing and even stopping) various chemical reactions, provided they are thermodynamically possible. This means that they are regulatory substances in the body of living beings , usually decreasing the initial energy required to start the reaction.
Enzymes are essential for life and catalyze around 4000 known chemical reactions , provided that the conditions of pH , temperature or chemical concentration are stable , since enzymes, being proteins, can also be denatured and lose their effectiveness.
The first enzyme was discovered in the mid-nineteenth century by Anselme Payen and Jean-Francois Persoz, although the experiments on the fermentation of Louis Pasteur had already sensed the presence of some “accelerating” organic substance in these processes, which by the time They were considered purely chemical.
Enzymes today are widely known and in fact used by various human industries (food, chemicals, agriculture, oil, etc.), in addition to being an indispensable part of the components that maintain the internal balance of our body , accelerating necessary reactions ( such as those that supply energy), activating and deactivating others selectively (as do hormones) and a varied and so on.
Most enzymes are composed of globular proteins of very variable size: from monomers of 62 amino acids, to huge chains of around 2500. However, only a few of them are directly involved in the catalysis of the reaction, known as active center .
The sequence in which all these amino acids are assembled determines the three-dimensional structure of the enzyme, which also dictates its specific functioning. Sometimes this structure also has sites to attract cofactors, that is, other substances whose intervention is necessary to produce the desired effect.
Enzymes are highly specific, that is, they do not react with anything or intervene in any reaction. They have a very punctual and precise biochemical role, which they carry out with a very low percentage of errors.
Enzymes are classified based on the specific reaction they catalyze, as follows:
Enzymes can operate differently, although always decreasing the activation energy of a chemical reaction, that is, the amount of energy needed to start it. These different modes are:
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